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Head, Translational Development Strategy (NCI)

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Job Number:
645178
Job Category:
Scientist / Research & Development
Location:
FREDERICK, MD US
Schedule:
Full-time
Travel:
None
Shift:
Day Job
Potential for Teleworking:
No
Clearance Level Must Currently Possess:
None
Clearance Level Must Be Able to Obtain:
Public Trust
Description:

Do you want to work with world renowned immunologists, cancer biologists and epidemiologists?  Would you like to facilitate the rapid movement of basic science findings to the clinical setting?  Does the challenge of establishing strategic partnerships with pharma intrigue you? If so we are looking for you.…..


This position will work in support of the Office of Translation Resources (OTR) within the Office of the Director (OD), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH).  In this role, you will have the opportunity to be a part of the world’s leading catalyst for tomorrow’s cancer research and patient treatments, and to improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient.


The successful translation of bench findings into therapeutics is a high priority. This process is high risk-high impact and is seldom possible within the confines of a single PI’s laboratory. Of the steps required, many are common to all drug development projects, but others are unique.  These research findings are varied from preclinical findings on small molecules to medical devices and techniques.  Multiple areas of expertise including chemistry, human subjects research, intellectual property, mouse study design, pharmacokinetics (PK), drug screening, and industrial project management, among others, must typically be brought to bear upon this process to achieve success and maintain timely progress.  In addition, such development can involve critical collaborations within NIH, with extramural partners and with industry.

The OTR serves as a unifying force for drug development and translational initiatives to facilitate the rapid translation of advances in basic science into successful therapeutics for cancer.  The OTR requires additional support to catalyze the development of preclinical discoveries with high-potential for translation for clinical use through strategic partnerships with industrial and other partners.  A critical part of the function is to strengthen communications/collaborations groups with strong translational interests located at the NCI-Frederick and it will require collaboration with the Molecular Targets Laboratory (MTL).


We are looking for an expert to serve as Head, Translational Development Strategy within the OTR. The major objective of this position is to develop, enable strategies that will facilitate the identification of partners who can collaborate with our PI’s to swiftly and effectively translate scientific discoveries toward clinical application. 

Major tasks will include:

  • Advise Principal Investigators and senior leadership on project based and organizational translational strategies for discoveries
  • Establish partnerships and strengthen communications/collaborations within and outside of NIH with biotech industry and groups with strong translational interests/expertise.  This includes continuing the close collaboration with the Molecular Targets Laboratory (MTL) in Frederick as well as increasing interactions with groups that can facilitate drug development and translational work such as those at NCATS, the NCI’s Division of Cancer Treatment and Diagnosis (DCTD) and with current and potential industry partners. 
  • Facilitate outreach to biotech/pharma partners for licensing CCR inventions.  Create outreach opportunities aimed at engaging PIs with potential drug development projects and providing guidance through the translational pipeline.
  • Identify strategic improvements in CCR technology and drug development process and infrastructure. 

This position does not represent a current opening but may be used to identify candidates with skills and experience for positions within Leidos Biomedical Research that will become available.  Candidates who express an interest will be considered for future positions at Leidos Biomedical Research.


Qualifications:

MINIMUM QUALIFICATIONS:

  • Ph.D. and/or M.D. from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a health science or related biomedical field, applicable to cancer research.
  • Foreign degrees must be evaluated for U.S. equivalency
  • Must have at least five years’ experience in biotechnology and/or drug development and broad knowledge of translational strategies applicable to cancer research.
  • The ideal candidate will have extensive diagnostic and therapeutic development experience in industry i.e. drugs, imaging technologies, cellular therapies and instrumentation and the demonstrated ability to work effectively with Principal Investigators (PIs). 
  • Must be able to obtain and maintain a security clearance

OTHER QUALIFICATIONS:

  • Broad knowledge and skill in commercial biomedical research technology development involved in using the applied knowledge of biology to advance biomedical research by developing products for human diseases and conditions, particularly cancer. 
  • Expert knowledge of industry drug development process, structure and milieu.
  • In-depth knowledge of the product and the development process.  Knowledge of the design, development and enhancement of current biomedical products and processes including new-product development, process optimization and process validation.  Thorough understanding of production processes and generally accepted industry practices. 
  • Ability to develop partnerships across research teams and with extramural and industry collaborators. 
  • Ability to develop partnerships across research teams and with extramural and industry collaborators.
  • Advanced knowledge of and skill in drug development and industrial pharmaceutical toxicology and safety assessment drug development.
  • Demonstrated skill in the design, coordination, analysis and documentation of preclinical studies.
  • Mastery of the methods and principles of medical and/or scientific research, as would typically be acquired through an advanced degree and additional training and professional experience in a health sciences, medical, or allied health field, such as biology, biological sciences, microbiology, pharmacology, toxicology, public health, medicine, or chemistry.  Such knowledge is used to review and advise the research community on opportunities and review requirements and instruments to satisfy program objectives related to drug development, technology transfer, protection of intellectual property, and licensing. 
  • Sound knowledge of molecular biology concepts.
  • Knowledge of the structure and functions of research institutions and the translation of research findings into technology and marketable health products.


Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an Equal Opportunity Employer.
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