Team Lead Single Cell Analysis Facility (NCI)

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Scientist / Research & Development
Day Job
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The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR).  The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and nextGen sequencing. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR).  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.


Team Lead Single Cell Analysis Facility

We are seeking a highly motivated Sr. Scientist to lead the newly established Single Cell Analysis Facility (SCAF) of the Center for Cancer Research (CCR) at NCI.  The SCAF will house state of the art single cell sequencing technologies including 10xGenomics Chromium, BD Genomics Rhapsody, DEPPArray, and other emerging single cell technologies.  Responsible for managing the single cell core activities

Will interact with close to 200 laboratories within the CCR to design and carry out single cell experiments for cancer research. 

In additional to the core activities:

  • Will be responsible for developing new single cell technologies and making it available for CCR community
  • Will train/guide staff to carry out wet lab experiment from tissue/cell preparation to NexGen sequencing
  • Work with dedicated bioinformaticians to perform data qc and analysis
  • Is expected to author publications in peer reviewed scientific journals



  • Possession of a Doctoral degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) appropriate to biomedical research (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency
  • In addition to educational requirements, a minimum of five (5) years of experience with NextGen sequencing including Single Cell Sequencing
  • Able to prepare detailed, concise technical reports, including assisting with publications
  • Strong laboratory skills
  • Must have strong single cell sequencing expertise, cell and molecular biology skills
  • Knowledge of cell dissociation and single cell isolation
  • Experience with NextGen sequencing and sequence analysis
  • Project management experience
  • Must be able to obtain and maintain a security clearance


Candidates with these desired skills will be given preferential consideration:

  • Broad background in molecular biology, cell biology, cancer biology and extensive knowledge and experience in NexGen sequencing, single cell sequencing including single cell preparation from various tissues, NexGen sequencing library preparation, data analysis and interpretation
  • Familiar with dropseq, 10xgenomics, Illumina ddseq or other single cell sequencing technologies
  • Familiar with the bioinformatics tools for single cell sequencing data analysis and have experience in interpreting single cell sequencing data

Expected Competencies:

  • Excellent written and verbal communication skills
  • Must be detail-oriented and able to manage multiple projects simultaneously
  • Able to work dynamically in a diverse team environment
  • Outstanding customer service skills and management skills
  • Strong team player and team builder

Leidos Overview:
Leidos is a global science and technology solutions leader working to solve the world’s toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company’s 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported pro forma annual revenues of approximately $10 billion for the fiscal year ended January 1, 2016 after giving effect to the recently completed combination of Leidos with Lockheed Martin's Information Systems & Global Solutions business (IS&GS). For more information, visit www.Leidos.com. The company’s diverse employees support vital missions for government and commercial customers. Qualified women, minorities, individuals with disabilities and protected veterans are encouraged to apply. Leidos will consider qualified applicants with criminal histories for employment in accordance with relevant Laws. Leidos is an Equal Opportunity Employer.
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